Preparation and Testing the Hyperthermia Property of Electrospun Micro and Nanofibers
Araz Boghozian
Department of Mechanical Engineering, California State Polytechnic University, Pomona, 3801 W Temple Avenue, Pomona, CA 91768, USA
Chris W. Draper
Department of Mechanical Engineering, California State Polytechnic University, Pomona, 3801 W Temple Avenue, Pomona, CA 91768, USA
Jose D. Jimenez
Department of Mechanical Engineering, California State Polytechnic University, Pomona, 3801 W Temple Avenue, Pomona, CA 91768, USA
Jesus Rodriguez
Department of Mechanical Engineering, California State Polytechnic University, Pomona, 3801 W Temple Avenue, Pomona, CA 91768, USA
Menooa Zohrabian
Department of Mechanical Engineering, California State Polytechnic University, Pomona, 3801 W Temple Avenue, Pomona, CA 91768, USA
Lihua Zhang
Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, NY 11973, USA
Yong X. Gan *
Department of Mechanical Engineering, California State Polytechnic University, Pomona, 3801 W Temple Avenue, Pomona, CA 91768, USA
*Author to whom correspondence should be addressed.
Abstract
The hyperthermia properties of nanomaterials have received attention in recent years due to the advances in nanofiber production. One of the main proponents is the medical field where it is used to combat malignant cancer cells. In this work we confirmed that a polymer solution containing titanium cobalt compounds as precursors can be electrospun into fibers and transformed into a ceramic oxide after heat treatment. After heat treatment the fiber size is reduced. The size of the fiber is in the range from nanoscale to the microscale. The fiber shows intensive hyperthermia behavior in the electromagnetic field. The temperature increases from 22 to 40°C when it is heated for 30 s. The surface temperature of the heat treated specimen increases less during the hyperthermia test as compared with that of the unheated specimen.
Keywords: Hyperthermia properties, nanomaterials, electrospinning fibers, titanium-cobalt oxide