Studies of Pharmaceutical Active Ingredients in Drugs through Radiological Parameters

A. Manjunath

Deparment of Physics, Gulbarga University, Gulbarga, Karnataka, India

B. R. Kerur *

Deparment of Physics, Gulbarga University, Gulbarga, Karnataka, India

*Author to whom correspondence should be addressed.


Abstract

Mass attenuation coefficient and effective atomic number of the active pharmaceutical ingredients viz, Alprazolam, Amiodar, Amiodarone, Ciprofloxacin, Diclofenac Sodium, Femotidine and Nimesulide have been calculated over a wide energy range from 1 keV to 100 GeV for total and partial photon interactions by using WinXCom. The obtained data shows that the change in mass attenuation coefficient and electron density varies with energy and chemical composition of the active pharmaceutical ingredients (API’s) in drugs. The results in the variation of photon interaction with energy and effective atomic number of the API’s in drug are shown in the logarithmic graphs.

 

Keywords: API, pharmaceutical, WiXCom, absorption edge


How to Cite

Manjunath, A., and B. R. Kerur. 2015. “Studies of Pharmaceutical Active Ingredients in Drugs through Radiological Parameters”. Physical Science International Journal 7 (3):186-91. https://doi.org/10.9734/PSIJ/2015/18029.

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